Elements Contrast Clearance Analysis
Assess Your Treatments with More Insights
Make the optimum treatment decision based on imaging analysis
Elements Contrast Clearance Analysis is an MRI-based methodology for the differentiation of contrast clearance and accumulation regions in brain tumor datasets. The high-resolution analysis results provide additional insights to support you during ongoing assessment and decision-making.
Demo Contrast Clearance Analysis
Clinical use & methodology
Developed at Sheba Medical Center in Tel Aviv, Contrast Clearance Analysis serves multiple clinical specialties including radiosurgery, radiation oncology, neurosurgery, neuro-oncology and neuroradiology.
High-resolution Contrast Clearance Analysis results derived from conventional 3D contrast-enhanced MRI data provide additional insights into tumor characteristics. These results enable the ongoing assessment of radiation effects versus tumor re-growth to support you in making the most appropriate decisions for initial and follow-up treatments.
The method requires the acquisition of two standard 3D T1-weighted MRIs—one 5 minutes and another 60-105 minutes after injection of a standard dose of contrast agent. The first series is intelligently subtracted from the second for Contrast Clearance Analysis. The analysis results are high-resolution, volumetric maps distinguishing regions of contrast clearance (blue) from contrast accumulation (red).
Learn more about Contrast Clearance Analysis
Peker et al. 2021
Read more about the use of treatment response assessment maps in discriminating between radiation effect and persistent tumoral lesion in metastatic brain tumors treated with gamma knife radiosurgery.Read more
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Contrast Clearance Analysis for Differentiating Tumor From Treatment Effects
Dheerendra Prasad, MD of Roswell Park Comprehensive Cancer Center, covers topics including the review of the role of Contrast Clearance Analysis in a high-volume brain radiosurgery practice, discusses modern challenges in the multimodality management of brain metastases and the integration of Elements in the Gamma Knife workflow and more.Watch now